Aceclofenac Paracetamol and Serratiopeptidase Tablets

Aceclofenac, Paracetamol, and Serratiopeptidase Tablets: Uses, Benefits, Dosage, and More

Introduction

Aceclofenac, Paracetamol, and Serratiopeptidase Tablets are a combination medication widely used in the treatment of pain, inflammation, and fever. This combination is particularly effective in conditions such as arthritis, musculoskeletal pain, dental pain, post-surgical pain, and other inflammatory disorders. The synergistic action of these three drugs provides potent analgesic (pain relief), antipyretic (fever-reducing), and anti-inflammatory effects, making it a popular choice among healthcare professionals.

Composition and Mechanism of Action

Each tablet of this combination typically contains:

• Aceclofenac (100 mg) – A non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation.
• Paracetamol (325 mg/500 mg) – A commonly used analgesic and antipyretic that enhances the pain-relieving effect of Aceclofenac.
• Serratiopeptidase (10 mg/15 mg) – An enzyme that helps in reducing swelling and inflammation by breaking down proteins involved in inflammation.

How These Ingredients Work Together

1. Aceclofenac works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins responsible for pain and inflammation.
2. Paracetamol primarily works on the central nervous system, reducing pain perception and lowering fever by acting on the hypothalamus.
3. Serratiopeptidase helps in breaking down inflammatory proteins, promoting faster healing, and reducing swelling in affected tissues.

Indications: Medical Uses of Aceclofenac, Paracetamol, and Serratiopeptidase Tablets

This combination medication is used in various conditions, including:

1. Musculoskeletal Pain and Inflammation

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Lower back pain
• Sprains and strains
• Gout

2. Post-Surgical and Post-Traumatic Pain

• Postoperative pain management
• Pain after dental procedures (tooth extraction, root canal treatment, etc.)
• Sports injuries and fractures

3. Ear, Nose, and Throat (ENT) Conditions

• Sinusitis
• Tonsillitis
• Pharyngitis

4. Fever and General Pain Relief

• Viral fever with body aches
• Headaches and migraines
• Menstrual cramps

Benefits of Aceclofenac, Paracetamol, and Serratiopeptidase Tablets

✅ Effective Pain Management – Provides faster and more sustained relief from pain and inflammation. ✅ Reduced Swelling and Inflammation – Serratiopeptidase helps in faster healing by reducing swelling. ✅ Improved Mobility – Beneficial for arthritis patients in reducing stiffness and improving joint movement. ✅ Fever Reduction – Paracetamol helps in lowering fever and discomfort. ✅ Safer than Other NSAIDs Alone – Combining these agents allows for lower doses, reducing the risk of side effects.

Dosage and Administration

Recommended Dosage

• Adults: 1 tablet twice daily (as prescribed by a doctor).
• Children: Not usually recommended unless prescribed by a healthcare professional.
• Elderly Patients: Dose adjustments may be required due to potential kidney or liver concerns.

How to Take This Medication

• Take the tablet after meals to avoid gastric irritation.
• Swallow the tablet whole with a glass of water; do not crush or chew.
• Maintain adequate hydration while on this medication.

Side Effects and Precautions

Common Side Effects

• Nausea and vomiting
• Stomach pain or acidity
• Dizziness
• Diarrhea or constipation
• Skin rashes (in rare cases)

Serious Side Effects (Seek Medical Help Immediately)

• Severe gastric ulcers or bleeding
• Liver damage (if taken in excess)
• Allergic reactions (swelling, difficulty breathing, severe rash)
• Kidney function impairment

Precautions to Take While Using This Medicine

• Avoid Alcohol – Alcohol can increase the risk of liver damage when taken with Paracetamol.
• Caution in Liver & Kidney Disorders – Patients with liver or kidney conditions should take this medication under strict medical supervision.
• Pregnancy & Breastfeeding – Should only be taken if prescribed by a doctor.
• Not Suitable for Patients with Ulcers – Can increase the risk of gastric bleeding.

Drug Interactions: What to Avoid?

This medicine may interact with certain drugs, including:

• Blood Thinners (Warfarin, Aspirin) – Increases the risk of bleeding.
• Corticosteroids (Prednisolone, Dexamethasone) – May enhance gastric irritation.
• Other NSAIDs (Ibuprofen, Diclofenac) – Increases the risk of stomach ulcers and kidney damage.
• Antibiotics (Rifampicin, Ciprofloxacin) – May interfere with drug metabolism.

Comparison with Other Pain Relievers

Aceclofenac vs. Diclofenac

• Aceclofenac is better tolerated than Diclofenac, with fewer gastrointestinal side effects.
• Provides longer-lasting pain relief than Diclofenac.

Aceclofenac + Paracetamol vs. Ibuprofen + Paracetamol

• Aceclofenac is more potent in reducing inflammation compared to Ibuprofen.
• The combination with Serratiopeptidase provides better anti-inflammatory benefits.

Storage and Handling

• Store in a cool, dry place away from direct sunlight.
• Keep out of reach of children.
• Check the expiry date before consumption.

Conclusion

Aceclofenac, Paracetamol, and Serratiopeptidase Tablets are an effective and well-tolerated combination for treating pain, fever, and inflammation. Their synergistic action makes them a preferred choice in orthopedics, dentistry, and post-operative care. However, it is essential to use this medication under medical supervision to prevent potential side effects. Always follow the prescribed dosage, take necessary precautions, and consult a doctor in case of adverse reactions.